Substance dependence (SD) is considered as an important health and psychological disorder with wide and serious psychosocial effects. Substance dependence is also an important contributor to both family and economic harms . Along with the social and demographic changes, SD is becoming a more serious health and social issue as the number of substance users is rising constantly among both adults and young individuals [2, 3]. Substance dependence is associated with a wide range of side effects such as sexually and blood transmitted diseases, depression and suicide, problems in interpersonal relationships and traffic related injuries or deaths [4, 5]. Depending on the age of starting substance use, the disorder also causes several cognitive, social, behavioral and other health problems . It is suggested that adverse effects of SD among young individuals are even more serious as over 90% of substance users who obtain their first experience of administering the substances during their adolescence, experience serious adverse health and psychological effects and socio-economic problems [4, 6, 7]. Based on a report from the united nations office on drug (UNODC), there are approximately 185 million substance users worldwide, 5% of whom (nearly 20 million) used substances for at least 1 year [2, 8,9,10]. It is estimated that 1.2 to 2% of drug users are living in Iran [3, 11]. More worryingly, possibly due to its geographical location, Iran is experiencing a sharp raise of SD [2, 3]. It is also worth noticing that SD among Iranian men is about ten times more common than women. It is possibly due to men’s easier social, cultural and financial access to the substances via attached social networks. Official reports suggest that opium, cocaine and heroin are the most common types of illicit drugs used in the country . In addition to opioids, chemosynthetic substances including oxy Sudan, hydro soudan, methadone, hydromorphone, meperidine and codeine are also widely used in Iran. Opioids are powerful pain killers which join to both central and environmental receptors  and cause some cognitive and socio-behavioral alterations including social disability, depression and anxiety among users [13, 14]. In addition to the individual affected side effects, drug trade activities including drug trafficking also has caused security and social crisis in Iran .
As the result of adverse health, social and financial effects of substance dependence in Iran, the issue of SD epidemic is of grate national concern [3, 8]. Due to variability and complexity of SD, the contributing factors are largely different between communities . In addition, despite the ease of becoming SD to different available substances, especially opioids, withdrawal is hard, complicated, lengthy and painful with a worryingly high rate of failure even after several years of staying clear of drugs. Although the painful symptoms among people in treatment for substance use disorder start few hours after the last usage of drug, they may last for about 1 month, after which the symptoms start weakening . Numerous studies suggested that depending on the type of used substances and method of administration, 20 to 90% of substance users use treatment and quitting procedures, though predominantly with no success . For example, a survey on a representative sample of Iranian population suggested that about 40% of opioids dependent individuals who were predominantly male, had 12 month of unmet treatment need . Among different methods of withdrawing SD, using alternative drugs including bupropion, medafinil, dextoam and phetamine is very common . Two other substances which are wildly used for treatment of SD among Iranian patients are methadone and methamphetamine. Previous studies suggested a sharp increase (6 to 20%) in the use of methamphetamine and methadone among Iranian withdrawers as alternative to opioids . However, solely treatment with methadone or methamphetamine is Longley and the drugs bring dependency too. This make treatment of SD even more complicated . Registering with residential rehabilitation centers is also among popular methods used by Iranian substance users to quit. Rehabilitation camps help patients in changing their social environment, provide them with better care and make them feel safer . These centers also play important roles in changing patient’s behavior and social networks which help them to increase the chance of successful treatment . It seems that many Iranian drug users try to stop substance use several times with different self-administered methods including remedies and treatment approaches. However, due to involvement of many psycho-social, financial and family factors in SD, most quitting attempts are failed and the patient starts substance use again . The patients then may try more advanced methods including registering in residential treatment camps. Few studies are conducted to investigate the related factors of quitting SD. For example, a study on characteristics of Iranian substance users who voluntarily introduced themselves to residual treatment centers suggested that most withdrawers were married, were literate and were employed . According to the results, most participants were trying to quit SD because of physical, psychological or financial problems. It was interesting that family encouragement and support was only the fourth reported reasons for quitting SD. Regarding the high prevalence of substance use and the sharp increase of SD  prevention and treatment of SD has become a strategic priority of Iranian government. The aim of this study was to identify factors which contribute to attempt to treat substance use disorder among males users in Yasuj the capital of Kohgilooyeh and Boyerahmad province.