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Table 4 Drug poisoning decedents with dispensed prescriptions for selected drug classes, by drugs involved in the drug poisoning deaths, and in relation to the day of the drug poisoning death (N = 2248)

From: Drugs involved in Kentucky drug poisoning deaths and relation with antecedent controlled substance prescription dispensing

Controlled substances, by classa

Deaths involving FENTANYL or HEROIN (N = 1573)

Deaths involving opioids other than FENTANYL or HEROIN (N = 223)

Deaths not involving opioidsb

(N = 452)

1 month prior

6 months prior

Since

2008

1 month prior

6 months prior

Since 2008

1 month prior

6 months prior

Since 2008

 N(%)

N(%)

N(%)

N(%)

N(%)

N(%)

N(%)

N(%)

N(%)

Buprenorphine MOUD

101(6.4)

222(14.1)

585(37.2)

16(7.2)

24(10.8)

53(23.8)

21(4.6)

38(8.4)

106(23.5)

Opioid Analgesics

123(7.8)

260(16.5)

1299(82.6)

83(37.2)

101(45.3)

196(87.9)

54(11.9)

98(21.7)

379(83.8)

Benzodiazepine

99(6.3)

135(8.6)

678(43.1)

43(19.3)

51(22.9)

140(62.8)

44(9.7)

61(13.5)

230(50.9)

Stimulants

25(1.6)

36(2.3)

141(9.0)

≤ 5

≤ 5

12(5.4)

8(1.8)

10(2.2)

38(8.4)

Muscle Relaxants

≤ 5

≤ 5

78(5.0)

0

0

31(13.9)

0

≤ 5

30(6.6)

Z-drugs

12(0.8)

18(1.1)

184(11.7)

≤ 5

7(3.1)

55(24.7)

6(1.3)

10(2.2)

77(17.0)

Gabapentinoids

123(7.8)

188(12.0)

449(28.5)

65(29.1)

82(36.8)

123(55.2)

55(12.2)

84(18.6)

156(34.5)

Any controlled subst.

340(6.0)

582(37.0)

1361(86.5)

120(53.8)

141(63.2)

203(91.0)

114(25.2)

177(39.2)

392(86.7)

  1. aDefinitions for selecting the drug products (MEDI-SPAN search criteria) are provided in Additional File 1
  2. bThese deaths involved only non-opioid drug(s) (e.g., methamphetamine n = 219, cocaine n = 31, gabapentin n = 30, alprazolam n = 11; not mutually exclusive: a death that involved both methamphetamine and gabapentin is counted under each drug)
  3. Note: The number of drug poisoning deaths with FENTANYL involvement was based on literal text analysis. There were 9 drug poisoning deaths involving FENTANYL that were not coded with an ICD-10 code for synthetic opioid and were not classified as opioid-involved deaths in Table 1
  4. Note: Counts greater than 0 but ≤ 5 were suppressed according to the state data reporting policy; Percentages are not reported in the case of a suppressed cell count