Table 1 Demographic and OAT data of the HCV treatment group and other HCV antibody positive OAT patients compared to each other and to the national OAT data [18]
Data from patient records | Comparative data | |||
|---|---|---|---|---|
HCV treatment group (n = 20) % [95% CI] | Other HCV antibody positive OAT patients (n = 215) % [95% CI] | P valuea | National OAT data (n = 836) [18] % (95% CI) | |
Gender | n = 20 | n = 215 | 0.751 | n = 836 |
Male | 65.0 [44.1,85.9] | 67.9 [61.7,74.1] | 71 [68,74] | |
Age | n = 20 | n = 215 | 0.083 | n = 836 |
Median (min, max) | 40 years (min 23, max 51) | 38 years (min 20, max 59) | 36 years (NA) | |
Under 30 years | 10.0 [0.0,23.1] | 14.9 [10.1,19.7] | 20 [17,23] | |
30-39 years | 25.0 [6.0,44.0] | 46.0 [39.3,52.7] | 45 [42,48] | |
40 years and older | 65.0 [44.1,85.9] | 39.0 [32.5,45.5] | 35 [32,38] | |
Education | n = 20 | n = 177 | 0.469 | n = 836 |
9 years or less | 65.0 [44.1,85.9] | 59.9 [52.7,67.1] | 61 [58,64] | |
More than 9 years | 30.0 [9.9,50.1] | 40.1 [32.9,47.3] | 33 [30,36] | |
Unknown | 5.0 [0.0,14.6] | 0.0 | 6 [4,8] | |
Housing | n = 20 | n = 178 | 0.452 | n = 836 |
Regular | 95.0 [85.4100] | 88.8 [84.2,93.4] | 81 [78,83.7] | |
Irregular | 5.0 [0.0,14.6] | 3.9 [1.1,6.7] | 17 [14,20] | |
Homeless | 0.0 | 7.3 [3.5,11.1] | 0 | |
Other or unknown | 0.0 | 0.0 | 2 [1,3] | |
Working status | n = 20 | n = 178 | 0.591 | n = 836 |
Regular | 10.0 [0,23.1] | 5.1 [1.9,8.3] | 6 [4,8] | |
Irregular | 0.0 | 3.4 [0.7,6.0] | 1 [0,2] | |
Rehabilitative work activities | 15.0 [0.0,30.7] | 9.6 [5.3,13.9] | 8 [6,10] | |
Unemployed | 45.0 [23.2,66.8] | 60.7 [53.5,67.9] | 55 [52,58] | |
Retired | 10.0 [0.0,23.1] | 5.1 [1.9,8.3] | 10 [8,12] | |
Other or unknown | 20.0 [2.4,37.5] | 16.3 [10.9,21.7] | 20 [17,23] | |
OAT treatment setting | n = 20 | n = 194 | 0.021 | n = 836 |
Inpatient | 0.0 | 24.7 [18.6,30.8] | 40 [37,43] | |
Outpatient | 100.0 | 75.3 [69.2,81.4] | 57 [54,60] | |
Unknown | 0.0 | 0.0 | 3 [2,4] | |
Concomitant substance use | n = 20 | n = 179 | n = 836 | |
Current use | 90.0 [76.9100] | 71.5 [64.9,78.1] | 0.083 | 55 [52,58] |
Current IV/IM use | 40.0 [18.5,61.5] | 48.6 [41.3,55.9] | 0.778 | 41 [38,44] |
Stimulants | 50.0 [28.1,71.9] | 38.5 [31.4,45.6] | 0.918 | 50 [47,53] |
Opioids | 5.0 [0.0,14.6] | 16.2 [10.8,21.6] | 0.109 | 46 [43,49] |
Other drugsb | 80.0 [62.5,97.5] | 55.9 [48.6,63.2] | 0.111 | NA |
Alcohol | 15.0 [0.0,30.7] | 16.8 [11.3,22.3] | 0.603 | 30 [27,33] |
OAT program | n = 20 | n = 169 | 0.898 | n = 836 |
Rehabilitative | 55.0 [33.2,76.8] | 59.8 [52.6,67.0] | 47 [44,50] | |
Harm-reducing | 45.0 [23.2,66.8] | 40.2 [33.0,47.4] | 45 [42,48] | |
Undefined or unknown | 0.0 | 0.0 | 8 [6,10] | |
Years in OAT | n = 19 | n = 194 | 0.983 | |
median (min … max) | 3 (min 0, max 17) | 3 (min 0, max 18) | NA | |
OAT medications (%) | n = 20 | n = 203 | 0.084 | n = 836 |
Methadone | 45.0 [23.2,66.8] | 51.7 [44.8,58.6] | 45 [42,48] | |
Buprenorphine-naloxone | 55.0 [33.2,76.8] | 48.3 [41.4,55.2] | 42 [39,45] | |
Other or unknown | 0.0 | 0.0 | 13 [11,15] | |
OAT median dose | n = 20 | n = 195 | ||
Methadone | 85 mg (min 45, max 160 mg) | 75 mg (min 20, max 150 mg) | 0.313 | NA |
Buprenorphine-naloxone | 16 mg (min 10, max 20 mg) | 16 mg (min 2, max 22 mg) | 0.551 | NA |
Years with HCV | n = 1 | n = 107 | ||
median (min … max) | 1 | 10 (min 0, max 29) | NA | |