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Table 1 Change in post-volume pre-COVID-19 and COVID-19 periods among leading substances discussed on opioid-related forums

From: Concerns among people who use opioids during the COVID-19 pandemic: a natural language processing analysis of social media posts

 

Pre-COVID-19 period daily average

COVID-19 period daily average

Difference

Change (%)

Medications for Opioid Use Disorder and Overdose Reversal

  Methadone

20.751

56.313

35.562

171.4%

  Naltrexone

1.087

2.451

1.364

125.5%

  Buprenorphine

18.426

36.225

17.800

96.6%

  Naloxone

1.680

3.116

1.436

85.5%

Other Substances used in Non-Medical Settings

  Iboga

0.520

1.175

0.655

125.9%

  Kratom

3.454

7.222

3.768

109.1%

Prescription and Illegal Opioids

  Hydrocodone

0.986

2.687

1.701

172.6%

  Fentanyl

9.506

25.404

15.898

167.2%

  Oxycodone

2.191

5.796

3.606

164.6%

  Other prescription opioids

1.605

3.687

2.083

129.8%

  Heroin

8.325

14.677

6.352

76.3%

  Carfentanil

0.325

0.411

0.086

26.5%

Other Medications

  Diphenhydraminea

0.341

0.927

0.586

171.8%

  Diazepam

0.504

1.324

0.820

162.9%

  Other benzodiazepines

4.791

11.178

6.388

133.3%

  Alprazolam

1.384

3.164

1.780

128.7%

  Dextromethorphana

0.146

0.291

0.145

99.4%

  Dextroamphetamine

1.252

2.131

0.879

70.2%

  1. Substances are ordered by percentage change within each medication grouping. Category of “other opioids” and “other benzodiazepines” represents all such medications not explicitly mentioned in the table. Counts are based on generic and trade names, and their common misspellings
  2. aDenotes substances available in over-the-counter forms