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Table 2 Estimated crude and adjusted odds ratios and 95% confidence intervals of prescription opioid positivity according to driver characteristics, marijuana positivity and alcohol positivity, 2011–16 Fatality Analysis Reporting System (FARS) and 2013–14 National Roadside Survey of Alcohol and Drug Use by Drivers (NRS)

From: Is marijuana use associated with decreased use of prescription opioids? Toxicological findings from two US national samples of drivers

Characteristic

FARSa

NRSb

Prescription Opioids

Crude OR (95% CI)

Adjusted OR (95% CI)

Prescription Opioidsc

Crude OR (95% CI)

Adjusted OR (95% CI)

Positive (n = 3278)

No. (%)

Negative (n = 44,324)

No. (%)

Positive (n = 341)

No. (%)d

Negative (n = 7540)

No. (%)d

Age (years)

 15–24

322 (9.8)

9975 (22.5)

Reference

Reference

29 (9.7)

2156 (28.9)

Reference

Reference

 25–39

1114 (34.0)

13388 (30.2)

2.58 (2.27, 2.93)

2.80 (2.44, 3.20)

118 (38.5)

2424 (33.2)

3.45 (2.02, 5.87)

3.77 (2.23, 6.38)

 40–64

1490 (45.5)

16105 (36.3)

2.87 (2.53, 3.24)

3.00 (2.63, 3.42)

154 (43.5)

2363 (32.7)

3.95 (2.45, 6.35)

4.16 (2.66, 6.50)

 ≥ 65

352 (10.7)

4856 (11.0)

2.25 (1.92, 2.62)

2.12 (1.79, 2.50)

27 (8.3)

406 (5.2)

4.75 (2.24, 10.06)

4.62 (2.19, 9.74)

Sex

 Male

2409 (73.5)

34,569 (78.0)

Reference

Reference

178 (52.0)

4349 (56.8)

Reference

Reference

 Female

869 (26.5)

9748 (22.0)

1.28 (1.18, 1.39)

1.25 (1.14, 1.36)

156 (48.0)

3092 (43.2)

1.21 (0.90, 1.64)

1.21 (0.91, 1.60)

Race/ethnicity

 Non-Hispanic White

2766 (92.5)

33,265 (83.2)

Reference

Reference

266 (77.2)

4737 (60.3)

Reference

Reference

 Non-Hispanic Black

159 (5.3)

4796 (12.0)

0.40 (0.34, 0.47)

0.36 (0.30, 0.42)

51 (19.0)

1508 (26.1)

0.57 (0.39, 0.83)

0.51 (0.35, 0.75)

 Other

65 (2.2)

1935 (4.8)

0.40 (0.32, 0.52)

0.47 (0.36, 0.60)

14 (3.8)

1216 (13.6)

0.22 (0.10, 0.49)

0.24 (0.11, 0.53)

Geographic region

 South

1688 (51.5)

19,166 (43.2)

Reference

Reference

92 (37.7)

1894 (41.3)

Reference

Reference

 Midwest

676 (20.6)

9711 (21.9)

1.17 (1.01, 1.34)

0.92 (0.78, 1.09)

91 (25.6)

1816 (20.3)

1.38 (0.87, 2.19)

1.36 (0.87, 2.14)

 Northeast

302 (9.2)

5057 (11.4)

1.48 (1.30, 1.67)

1.29 (1.10, 1.51)

73 (21.6)

1379 (17.3)

1.37 (0.83, 2.28)

1.22 (0.73, 2.04)

 West

612 (18.7)

10,390 (23.4)

0.99 (0.86, 1.14)

0.81 (0.68, 0.96)

85 (15.1)

2451 (21.1)

0.78 (0.47, 1.30)

1.02 (0.64, 1.63)

Testing positive for marijuana

 No

2751 (83.9)

37,396 (84.4)

Reference

Reference

305 (88.0)

7020 (92.3)

Reference

Reference

 Yes

527 (16.1)

6928 (15.6)

1.03 (0.94, 1.14)

1.28 (1.15, 1.42)

36 (12.0)

520 (7.7)

1.62 (1.04, 2.51)

2.03 (1.29, 3.20)

Testing positive for alcohol

 No

2170 (66.2)

25,436 (57.4)

Reference

Reference

326 (97.3)

7134 (94.6)

Reference

Reference

 Yes

1108 (33.8)

18,888 (42.6)

0.69 (0.64, 0.74)

0.68 (0.63, 0.74)

15 (2.7)

406 (5.4)

0.50 (0.22, 1.14)

0.56 (0.24, 1.31)

  1. aThere were 7 drivers with missing data on gender and 4616 on race from the FARS
  2. bThere were 204 drivers with missing data on age, 106 on gender, and 89 on race from the NRS
  3. cUnweighted frequencies of drivers by prescription opioid testing results in the sample
  4. dPercentage of drivers weighted for the US driver population