|
Variables
|
Placebo group (n = 25)
|
Crocin group (n = 25)
|
Difference in outcome measures between crocin and placebo treatment groupsa
|
|---|
|
Baseline
|
Week 8
|
Baseline
|
Week 8
|
β (95% CI)
|
P
b
|
|---|
|
BDI score
|
23.6 ± 6.6
|
24.7 ± 7.3
|
22.8 ± 5.4
|
17.6 ± 5.0
|
−6.66 (−9.88,-3.45)
|
< 0.0001
|
|
BAI score
|
19.2 ± 4.0
|
19.2 ± 3.5
|
19.7 ± 6.6
|
15.3 ± 5.2
|
−4.35 (−5.94, −2.75)
|
< 0.0001
|
|
GHQ score
|
35.6 ± 13.0
|
34.4 ± 12.23
|
34.8 ± 11.5
|
29.3 ± 10.2
|
−4.45 (−7.68, −1.22)
|
0.008
|
|
PSQI
|
6.7 ± 2.3
|
7.0 ± 2.6
|
6.4 ± 2.3
|
4.1 ± 1.8
|
−2.73 (−3.74, −1.73)
|
< 0.0001
|
|
IIEF
|
22.0 ± 11.8
|
21.6 ± 12.1
|
21.0 ± 16.7
|
25.64 ± 16.5
|
4.98 (2.08, 7.88)
|
0.001
|
- Data are mean ± SDs
- a“Outcome measures” refers to the change in values of measures of interest between baseline and week 8. β [difference in the mean outcomes measures between treatment groups (crocin group = 1 and placebo group = 0)]
- bObtained from multiple regression model (adjusted for baseline age and BMI)
- BDI Beck Depression Inventory, BAI Beck Anxiety Inventory, GHQ general health questionnaire, IIEF International Index of Erectile Functions, PSQI Pittsburgh Sleep Quality Index
