Factors associated with health-related quality of life in a large national sample of patients receiving opioid substitution treatment in Germany: A cross-sectional study

Table 4 Multivariate linear regression models of sociodemographic and clinical variables with HRQOL in OST patients (n = 1703)

	Physical Composite Score (PCS) Adjusted R² = .206			Mental Composite Score (MCS) Adjusted R² = .181
	B (95% CI)	Beta	p	B (95% CI)	Beta	p
Gender	.00 (-.95 – .96)	.00	.99	-1.91 (-3.04 – -.77)	-.08	.001
Duration of opioid dependence (years)	-.18 (-.24 – -.13)	-.17	<.001	.05 (-.02 – .11)	.04	.13
Substitution medication	1.75 (.73 – 2.77)	.08	.001	1.60 (.38 – 2.82)	.06	.010
Employment	-2.11 (-2.47 – -1.75)	-.28	<.001	-1.56 (-1.99 – -1.13)	-.17	<.001
Living together with children	-.50 (-1.63 – .62)	-.02	.38	-1.39 (-2.74 – -.05)	-.05	.042
Relationship	.19 (-.31 – .68)	.02	.38	.13 (-.46 – .72)	.01	.66
Migration background	.34 (-.67 – 1.34)	.02	.51	1.17 (-.02 – 2.37)	.04	.06
Percentage of positive urine samples	-.01 (-.02 – .04)	-.02	.46	-.05 (-.08 – -.02)	-.08	<.001
Time in current OST	-.00 (-.01 – .00)	-.02	.34	.00 (-.00 – .01)	.02	.33
HIV status	2.1 (-.38 – 4.53)	.04	.10	1.38 (-1.56 – 4.31)	.02	.36
HCV status	-1.0 (-1.56 – -.48)	-.09	<.001	-.42 (-1.06 – .23)	-.03	.20
Psychiatric diagnoses	1.68 (.72 – 2.65)	.09	.001	4.73 (3.58 – 5.89)	.21	<.001
Psychopharmacological treatment	.85 (-.20 – 1.89)	.04	.11	3.12 (1.87 – 4.37)	.12	<.001

Note. Significant predictors are highlighted in bold. Variable codings and ranges are listed here. Gender: 1 = Male, 2 = Female; Duration of opioid dependence (years), range: 0 – 48; Substitution medication: 1 = D-/L-Methadone, 2 = Buprenorphine; Employment: 1 = Full time/education/training, 2 = Part time, 3 = Occasional /other, 4 = Unemployed; Living together with children: 1 = Yes, 2 = No; Partnership: 1 = Single, 2 = Relationship, not living together, 3 = Relationship, living together; Migration background: 1 = Yes, 2 = No; Percentage of positive urine samples, range: 0 – 100; Duration of current OST (months), range: 0 – 318; HIV status: 1 = Positive, 2 = Negative/unclear; HCV status: 1 = Anti-HCV - , 2 = Anti-HCV +/ RNA - , 3 = Anti-HCV +/ RNA + ; Psychiatric diagnoses: 1 = One or more, 2 = None; Psychopharmacological treatment: 1 = Yes, 2 = No.

ISSN: 1747-597X