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Table 1 Baseline characteristics and Cox regression analysis for factors associated with injection initiation among street-involved youth (n = 462)

From: Inability to access addiction treatment predicts injection initiation among street-involved youth in a Canadian setting

Characteristic

Baseline Characteristics

Bivariable and Multivariable Cox Regression Analysis

Injection Initiation

Unadjusted HRa

p-value

Adjusted HR (95 % CI)

p-valuef

Yes (n = 97) n (%)

No (n = 365) n (%)

(95 % CI)b

Unable to access addiction treatment d,e

    

 Yes

15 (15.5)

33 (9.0)

2.19 (1.27–3.78)

0.005

2.02 (1.12–3.62)

0.019

 No

80 (82.5)

324 (88.8)

    

Years since initiated hard drug use (HR per additional year)

  

 Median

5.4

5.4

1.00 (0.94–1.07)

0.893

0.99 (0.92–1.06)

0.714

 IQR

(3.7–7.8)

(3.1–7.9)

    

Caucasian Ethnicity

      

 Yes

68 (70.1)

219 (60.0)

1.50 (0.97–2.31)

0.069

1.40 (0.88–2.21)

0.152

 No

29 (29.9)

146 (40.0)

    

Female Gender

      

 Yes

28 (28.9)

114 (31.2)

0.96 (0.62–1.50)

0.872

1.06 (0.68–1.65)

0.805

 No

69 (71.1)

251 (68.8)

    

Heroin Usec,d,e

     

 Yes

24 (24.7)

52 (14.2)

2.12 (1.34–3.36)

0.001

1.48 (0.86–2.55)

0.157

 No

70 (72.2)

307 (84.1)

    

Cocaine Usec,d,e

     

 Yes

43 (44.3)

186 (51.0)

1.17 (0.77–1.78)

0.449

1.06 (0.69–1.64)

0.782

 No

52 (53.6)

176 (48.2)

    

Crack Smokingd,e

     

 Yes

68 (70.1)

190 (52.1)

1.71 (1.11–2.63)

0.015

1.23 (0.76–1.97)

0.402

 No

27 (27.8)

171 (46.8)

    

Crystal Meth Usec,d,e

     

 Yes

51 (52.6)

122 (33.4)

2.31 (1.53–3.47)

<0.001

2.00 (1.32–3.04)

0.001

 No

43 (44.3)

238 (65.2)

    
  1. Not all cells add up to 462 as participants may choose not to answer sensitive questions
  2. a HR hazard ratio; b CI confidence interval
  3. cdenotes non-injection use; ddenotes activities in the 6 months prior to follow-up interview; erefers to the activities lagged to the pervious available study follow-up; f p-values based on Wald test