serum or plasma
|
decreased
|
Sadlik J. et al., 2000 (humans – in case of heroin users; tendency to normalize upon detoxification treatment, but not reaching levels in control group) [44]
|
Elnimr T. et al., 1999 (humans – correlated with the abuse period) [45]
|
Ruiz Martinez M. et al., 1999 (humans – accompanied by increased copper) [46]
|
Iyengar V. et al., 1994 (humans – due to increased renal elimination) [69]
|
increased
|
Floriańczyk B., 2000 (mice, morphine) [77]
|
red blood cells
|
decreased
|
Ruiz Martinez M. et al., 1999 (humans) [46]
|
cerebrospinal fluid
|
decreased
|
Potkin S.G. et al., 1982 (humans) [47]
|
other tissues
|
brain
|
decreased
|
Floriańczyk B., 2000 (mice, morphine) [77]
|
Gulya K. et al., 1991 (rats) (parietal cortex, hippocampus and striatum) – induced by the δ- agonist (D-Pen2, D-Pen5)enkephalin, antagonized by naloxon [11]
|
liver
|
increased
|
Hidalgo J. et al., 1991 (rats, morphine) [75]
|
decreased
|
Floriańczyk B., 2000 (mice, morphine) [77]
|
lungs, kidney
|
decreased
|
Floriańczyk B., 2000 (mice, morphine) [77]
|
heart, spleen, muscle
|
increased
|
Floriańczyk B., 2000 (mice, morphine) [77]
|