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Table 3 Retention and illicit heroin use by randomization arm

From: Differential long-term outcomes for voluntary and involuntary transition from injection to oral opioid maintenance treatment

Outcome

Injectablec(n = 139)

Oralc(n = 106)

Injectable vs Oral

P Value

   

Relative risk (95% CI)

 

Retentiona

    

12 months

123 (88.5%)

60 (56.6%)

1.56 (1.31, 1.87)

<0.0001d

24 months

77 (55.4%)

60 (56.6%)

0.98 (0.78, 1.22)

0.851e

   

Mean difference (95% CI)

 

Illicit heroin useb

    

12 months

5.23 (3.43, 7.04)

11.99 (9.91, 14.07)

-6.76 (-9.49, -4.02)

<0.0001f

24 months

9.78 (7.71, 11.85)

11.48 (9.1, 13.87)

-1.7 (-4.87, 1.47)

0.291g

  1. All analysis are intention to treat.
  2. (a)No missing data.
  3. (b)With multiple imputation.
  4. (c)Numbers are: Mean (95% Confidence Interval) or N (%).
  5. (d)Chi-square test (chi-square value = 32.25, df = 1).
  6. (e)Chi-square test (chi-square value = 0.04, df = 1).
  7. (f)t-test, t-value = -4.87, adjusted degrees of freedom for multiple imputation = 240.6.
  8. (g)t-test, t-value = -1.06, adjusted degrees of freedom for multiple imputation = 159.3.