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Table 3 Retention and illicit heroin use by randomization arm

From: Differential long-term outcomes for voluntary and involuntary transition from injection to oral opioid maintenance treatment

Outcome Injectablec(n = 139) Oralc(n = 106) Injectable vs Oral P Value
    Relative risk (95% CI)  
Retentiona     
12 months 123 (88.5%) 60 (56.6%) 1.56 (1.31, 1.87) <0.0001d
24 months 77 (55.4%) 60 (56.6%) 0.98 (0.78, 1.22) 0.851e
    Mean difference (95% CI)  
Illicit heroin useb     
12 months 5.23 (3.43, 7.04) 11.99 (9.91, 14.07) -6.76 (-9.49, -4.02) <0.0001f
24 months 9.78 (7.71, 11.85) 11.48 (9.1, 13.87) -1.7 (-4.87, 1.47) 0.291g
  1. All analysis are intention to treat.
  2. (a)No missing data.
  3. (b)With multiple imputation.
  4. (c)Numbers are: Mean (95% Confidence Interval) or N (%).
  5. (d)Chi-square test (chi-square value = 32.25, df = 1).
  6. (e)Chi-square test (chi-square value = 0.04, df = 1).
  7. (f)t-test, t-value = -4.87, adjusted degrees of freedom for multiple imputation = 240.6.
  8. (g)t-test, t-value = -1.06, adjusted degrees of freedom for multiple imputation = 159.3.