Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan

Table 6 Factors associated with methadone-drug interactions (MDIs) among the co-medication subpopulation in the MMTP (128 patients)

Characteristics	Adjusted OR (95% CI)	*P-value*
Age	0.94 (0.88 ~ 0.99)	0.07
Sex
Female	1.00	-
Male	4.88 (1.25 ~ 20.17)	0.02*
Marital status
Married or living with partner	1.00	-
Divorced/widowed	2.24 (0.71 ~ 7.94)	0.19
Current illicit drug use
Heroin (yes vs. no)	0.38 (0.15 ~ 0.94)	0.04*
Number of comedications per MMTP participation months^a	1.41 (1.17 ~ 1.79)	0.002*

Stepwise logistic regression analysis was performed to identify associations of predictive variables
^aThe number of comedications per MMTP participation months: MMT participation period for each patient divided by the total number of comedications
OR = odds ratio.
*: < 0.05; **: < 0.0001

ISSN: 1747-597X