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Table 2 Selected characteristics of co-medication subpopulation in the MMTP (128 patients) according to the presence or absence of methadone-drug interactions (MDIs)

From: Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan

  No interaction (n = 43) Drug interaction (n = 85) df P-value*
Mean age, (SD) 40.7 (6.8) 39.0 (7.4) 127 0.20
Male, n (%) 36 (83.7) 75 (88.2) 1 0.47
Mean body mass index, kg/m2 (SD) 23.6 (3.3) 24.4 (3.9) 125 0.24
Education, n (%)     
   Less than high school 26 (60.5) 47 (55.3) 1 0.58
   High school or above 17 (39.5) 38 (44.7)   
Marital status, n (%)     
   Married or living with partner 13 (30.2) 27 (32.1) 2 0.69
   Never married 24 (55.8) 41 (48.8)   
   Divorced/widowed 6 (14.0) 16 (19.1)   
Employment, n (%)     
   Employed 30 (69.8) 55 (64.7) 1 0.57
   Other 13 (30.2) 30 (35.3)   
Current illicit drug use, n (%)     
   Heroin 22 (51.2) 30 (35.3) 1 0.08
   Amphetamine(s) 1 (2.3) 3 (3.5) 1 0.99
   Benzodiazepine(s) 7 (16.3) 14 (16.5) 1 0.98
Heroin use years, (SD) 9.5 (6.3) 7.6 (5.1) 119 0.11
Drug use in the past, n (%)     
   Heroin 43 (100) 85 (100) 1 --
   Amphetamine(s) 26 (60.5) 56 (65.9) 1 0.55
   MDMA 0 (0.0) 8 (9.4) 1 0.05
   Ketamine 1 (2.3) 10 (11.8) 1 0.10
Other substance use, n (%)     
   Cigarettes 33 (83.7) 73 (85.9) 1 0.75
   Alcohol 13 (30.2) 30 (35.3) 1 0.57
   Betel quid 9 (20.9) 28 (32.9) 1 0.16
HCV coinfection, n (%) 42 (97.7) 79 (92.9) 1 0.42
HBV coinfection (HBsAg-positive), n (%) 9 (20.9) 18 (21.2) 1 0.97
Current methadone dose, mg (SD) 53.9 (25.7) 53.0 (29.7) 127 0.86
MMTP participation period, months (SD) 17.7 (12.5) 22.8 (13.8) 126 0.04*
  1. *: statistical significance set at p < 0.05; Comparisons performed by the Mann-Whitney U test, Chi-square test or Fisher's exact test when appropriate