22 mg) of buprenorphine to the combination product, dose adjustments may be necessary especially in the later phase of the treatment. We recommend that a transfer from Subutex to Suboxone should be carefully discussed and planned in advance with the patients and after the transfer adverse events should be regularly monitored. With regard of buprenorphine IV abuse, the combination product seems to have a less abuse potential than buprenorphine alone."/>
Skip to main content

Table 2 Induction and transfer dose (n = 64)

From: A retrospective evaluation of patients switched from buprenorphine (subutex) to the buprenorphine/naloxone combination (suboxone)

  n (%)
Switched to same dose of Suboxone as Subutex 58 (90.6)
Switched to higher dose of Suboxone than Subutex 1 (1.6)
Switched to lower dose of Suboxone than Subutex 2 (3.1)
Titrated with Subutex during switch 3 (4.7)
  1. a59 patients reported history of heroin use