| Unadjusted regression | Partially adjusted regression a | Fully adjusted regression b | ||||||
---|---|---|---|---|---|---|---|---|---|
 | IRR | 95% CI | p-value | IRR | 95% CI | p-value | IRR | 95% CI | p-value |
Social deprivation | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Q1 (least deprived) | 1 | Â | Â | 1 | Â | Â | 1 | Â | Â |
Q2 | 0.81 | 0.21, 2.55 | 0.7 | 0.72 | 0.22, 2.17 | 0.6 | 0.85 | 0.24, 2.81 | 0.8 |
Q3Â (most deprived) | 0.44 | 0.12, 1.33 | 0.2 | 0.77 | 0.24, 2.30 | 0.6 | 0.92 | 0.25, 3.22 | 0.9 |
no LSOA | 0.80 | 0.19, 2.93 | 0.7 | 0.79 | 0.22, 2.70 | 0.7 | 0.31 | 0.06, 1.56 | 0.2 |
Recorded mental health comorbidity | Â | Â | Â | Â | Â | Â | Â | Â | Â |
No recorded diagnosis | 1 | Â | Â | 1 | Â | Â | 1 | Â | Â |
One recorded mental health diagnosis | 8.95 | 2.27, 55.2 | 0.005 | 9.08 | 2.29, 56.0 | 0.005 | 8.92 | 1.81, 64.4 | 0.007 |
Non-opioid substance use diagnosis | 4.46 | 2.15, 9.51 | < 0.001 | 4.53 | 2.14, 9.92 | < 0.001 | 3.91 | 1.74, 9.14 | < 0.001 |
Multiple recorded diagnosis | 17.9 | 7.18, 50.4 | < 0.001 | 17.9 | 6.86, 52.3 | < 0.001 | 15.9 | 5.89, 47.5 | < 0.001 |