AUC (95% CI) | Difference in AUC (95% CI)a | ||||||
---|---|---|---|---|---|---|---|
Substance | 18–25 | 26–34 | 35–49 | 50–70 | 26–34 vs. 18–25 | 35–49 vs. 18–25 | 50–70 vs. 18–25 |
Tobacco | 0.96 (0.93, 0.98) | 0.97 (0.96, 0.98) | 0.96 (0.94, 0.98) | 0.96 (0.94, 0.97) | 0.01 (-0.01, 0.04) | 0.00 (-0.03, 0.03) | 0.00 (-0.03, 0.03) |
Alcohol | 0.88 (0.83, 0.92) | 0.83 (0.78, 0.87) | 0.86 (0.82, 0.90) | 0.89 (0.84, 0.94) | -0.05 (-0.12, 0.01) | -0.02 (-0.08, 0.05) | 0.01 (-0.06, 0.08) |
Cannabis | 0.91 (0.87, 0.96) | 0.93 (0.90, 0.96) | 0.93 (0.91, 0.96) | 0.98 (0.96, 1.00) | 0.02 (-0.04, 0.07) | 0.02 (-0.03, 0.08) | 0.06 (0.01, 0.11) |
Cannabis (8 + threshold) | 0.92 (0.87, 0.97) | 0.94 (0.91, 0.97) | 0.95 (0.92, 0.98) | 0.95 (0.91, 0.99) | 0.02 (-0.04, 0.08) | 0.03 (-0.03, 0.09) | 0.03 (-0.04, 0.09) |
Sedatives | 0.99 (0.97, 1.02) | 0.96 (0.90, 1.02) | 0.96 (0.90, 1.01) | 0.94 (0.89, 0.98) | -0.03 (-0.10, 0.29) | -0.04 (-0.09, 0.24) | -0.05 (-0.11, -0.00) |
Prescription stimulants | 0.89 (0.81, 0.96) | 0.92 (0.86, 0.98) | 0.97 (0.94, 1.01) | 0.98 (0.93, 1.02) | 0.03 (-0.06, 0.13) | 0.09 (0.01, 0.17) | 0.09 (0.00, 0.18) |
Prescription painkillers | 0.84 (0.67, 1.01) | 0.95 (0.87, 1.03) | 0.91 (0.83, 0.98) | 0.95 (0.89, 1.01) | 0.11 (-0.08, 0.30) | 0.07 (-0.12, 0.26) | 0.11 (-0.07, 0.29) |