Association between toxic drug events and encephalopathy in British Columbia, Canada: a cross-sectional analysis

Table 1 Characteristics by encephalopathy diagnostic code (column %)

	Total (N = 824,165)		Encephalopathy diagnosis (N = 369)		No encephalopathy diagnosis (N = 823,796)
	N	%	N	%	N	%	p-value
Drug toxicity event (overdose), fatal or non-fatal
Yes	5,357	0.6	54	14.6	5,303	0.6	p < 0.01
No	818,808	99.4	315	85.4	818,493	99.4	p < 0.01
Age ^a
<30 years	197,378	23.9	41	11.1	197,337	24.0	p < 0.01
30–39 years	149,377	18.1	31	8.4	149,346	18.1
40–49 years	141,428	17.2	63	17.1	141,356	17.2
≥ 50 years	335,991	40.8	234	63.4	335,757	40.8
Sex
Female	414,959	50.3	135	36.6	414,824	50.4	p < 0.01
Male	409,206	49.7	234	63.4	408,972	49.6	p < 0.01
Mental illness ^b
No SUD or mental illness	677,154	82.2	144	39.0	677,010	82.2	p < 0.01
SUD	7,145	0.9	22	6.0	7,123	0.9
Mental illness	128,312	15.6	132	35.8	128,180	15.6
SUD and mental illness	11,554	1.4	71	19.2	11,483	1.4
Number of drug toxicity events
1 toxic drug event	3,623	0.4	35	9.5	3,588	0.4	p < 0.01
2 or more toxic drug events	1,734	0.2	19	5.2	1,715	0.2
None	818,808	99.4	315	85.4	818,493	99.4
Fatal drug toxicity
Yes	229	0.0	8	2.2	221	0.0	p < 0.01
No	823,939	100.0	361	97.8	823,575	100.0	p < 0.01

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